Abstract
In the preregistration trial, data on efficacy of BNT162b2 mRNA vaccine against SARS-CoV-2 infection were not collected. This study aimed to evaluate vaccine effectiveness (VE) against documented infection. Bari Policlinico University Hospital health care workers (HCWs) who completed the vaccination schedule were matched with HCWs who had refused vaccination. VE for documented infection was 61.9% (95% confidence interval [CI], 19.2%-82.0%) 14-20 days after first dose, 87.9% (95% CI, 51.7%-97.0%) 21-27 days after first dose, and 96.0% (95% CI, 82.2%-99.1%) 7 or more days after second dose. Unvaccinated HCWs remain a concern in the context of the pandemic emergency.
Keywords: COVID-19; documented infection; healthcare workers; vaccine effectiveness.
【저자키워드】 COVID-19, Healthcare workers, vaccine effectiveness, documented infection, 【초록키워드】 Efficacy, Vaccine, vaccination, pandemic, Trial, mRNA vaccine, SARS-COV-2 infection, Infection, HCWs, healthcare, Effectiveness, Health care worker, university, HCW, 95% CI, 95% confidence interval, second dose, first dose, vaccination schedule, collected, evaluate, of BNT162b2, 【제목키워드】 SARS-CoV-2, prevention, BNT162b2 mRNA, report,