Abstract
Purpose: Coronavirus disease 2019 (COVID-19) has placed a great burden on critical care services worldwide. Data regarding critically ill COVID-19 patients and their demand of critical care services outside of initial COVID-19 epicenters are lacking. This study described clinical characteristics and outcomes of critically ill COVID-19 patients and the capacity of a COVID-19-dedicated intensive care unit (ICU) in Kobe, Japan.
Methods: This retrospective observational study included critically ill COVID-19 patients admitted to a 14-bed COVID-19-dedicated ICU in Kobe between March 3, 2020 and June 21, 2020. Clinical and daily ICU occupancy data were obtained from electrical medical records. The last follow-up day was June 28, 2020.
Results: Of 32 patients included, the median hospital follow-up period was 27 (interquartile range 19-50) days. The median age was 68 (57-76) years; 23 (72%) were men and 25 (78%) had at least one comorbidity. Nineteen (59%) patients received invasive mechanical ventilation for a median duration of 14 (8-27) days. Until all patients were discharged from the ICU on June 5, 2020, the median daily ICU occupancy was 50% (36-71%). As of June 28, 2020, six (19%) died during hospitalization. Of 26 (81%) survivors, 23 (72%) were discharged from the hospital and three (9%) remained in the hospital.
Conclusion: During the first months of the outbreak in Kobe, most critically ill patients were men aged ≥ 60 years with at least one comorbidity and on mechanical ventilation; the ICU capacity was not strained, and the case-fatality rate was 19%.
Keywords: Bed occupancy; Coronavirus; Critical care; Mortality; Respiration, artificial; Respiratory distress syndrome, adult; Severe acute respiratory syndrome coronavirus 2.
【저자키워드】 coronavirus, Critical care, Mortality, Respiratory distress syndrome, adult, Severe acute respiratory syndrome coronavirus 2., Bed occupancy, Respiration, artificial, 【초록키워드】 COVID-19, Respiratory distress syndrome, Coronavirus disease 2019, intensive care, Hospitalization, Clinical characteristics, hospital, Comorbidity, outcome, ICU, Critically ill, Survivors, outbreak, clinical, Patient, Japan, Respiration, Follow-up, retrospective, Invasive mechanical ventilation, COVID-19 patient, medical records, Critically ill patient, interquartile range, acute respiratory syndrome, follow-up period, median age, Kobe, men, initial, described, died, remained, median, electrical, discharged, strained, the median, 【제목키워드】 outcome, Characteristics, clinical, retrospective, Critically ill patient, single-center, Kobe, with COVID-19,