Context: The Global Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) pandemic has resulted in explosive patterns of transmission in most countries. Nasopharyngeal swabs were the specimen’s collection tools recommended for the diagnosis of SARS-CoV-2 infection, and for monitoring infection outbreaks in communities. Our objective was to report the quality and efficacy of unsupervised self-collected mid turbinate “dry FLOQSwabs” (MT FLOQSwabs) (56380CS01, Copan). There were 111 specimens collected for the study: 36 by health care personnel, from themselves, to verify the quality and efficacy of mid-turbinate swabs; 75 to compare and assess the diagnostic performance, among health care personnel, of nasopharyngeal swabs and self-collected mid-turbinate FLOQSwabs. A collection of 51 specimens was enrolled to define the efficacy of the Testami program (validation). Our analyses demonstrate that self-collected mid-turbinate dry swabs ensure an accuracy of 97.3%, as compared to the standard nasopharyngeal swabs collected by health care workers. Furthermore, the mid-turbinate FLOQSwabs can be stored without medium for six days at room temperature without affecting the molecular diagnosis of the SARS-CoV-2 virus infection. Self-collection of diagnostic specimens at home could offer an avenue to increase testing availability for SARS-CoV-2 infection without asking people to travel to a clinic or a laboratory, thus reducing people’s exposure to infection. Our findings demonstrate that unsupervised self-collection swabs, transported dry, are sensitive, practical and easy-to-use tools and should be considered for diagnosis of SARS-COV-2 and coronavirus disease 2019 (COVID-19) surveillance.
【저자키워드】 SARS-CoV-2, Surveillance, dry swab, unsupervised self-collection, 【초록키워드】 COVID-19, coronavirus disease, Coronavirus disease 2019, Efficacy, pandemic, Health care, SARS-COV-2 infection, health care workers, Infection, diagnostic, Diagnosis, SARS-CoV-2 virus, Transmission, severe acute respiratory syndrome coronavirus-2, Laboratory, Nasopharyngeal swab, Health, Molecular diagnosis, Accuracy, outbreak, nasopharyngeal swabs, swabs, Travel, temperature, Swab, virus infection, respiratory, Care, Analysis, exposure to, room temperature, acute respiratory syndrome, medium, clinic, specimen, SARS-CoV-2 virus infection, offer, enrolled, collected, reducing, to define, without affecting, transported, diagnosis of SARS-CoV-2, the SARS-CoV-2 virus, 【제목키워드】 COVID-19,