Abstract
Purpose: Due to stay-at-home orders during COVID-19, we transitioned supervised, group, in-person resistance training interventions in two clinical trials in cancer survivors to live, online delivery using video-conferencing technology. We describe the feasibility, preliminary efficacy, and safety of live online group training and compare to in-person training.
Methods: Adherence (% sessions attended), retention (% participants completing intervention), and safety (# adverse events) data of resistance training groups from two randomized controlled trials in cancer survivors that participated before or during the COVID-19 pandemic were collated. Participants were post-treatment breast cancer survivors and their spouses (n = 62) and prostate cancer survivors (n = 32) (age range: 38-82 years). During COVID-19, delivery of supervised, group resistance exercise sessions was delivered live online via video-conference. Preliminary evidence for training efficacy was assessed by chair stand performance over the 6-month intervention.
Results: Feasibility of online resistance training was better than in-person for both studies (adherence: 86% vs 82% and 91% vs. 81% and retention 95% vs. 80% and 92% vs. 84% for online and in-person classes). Improvements in chair stand time were similar in prostate cancer and spouse groups that trained online vs. in-person, except for breast cancer survivors who improved more with in-person training (7% vs. 14% for online vs. in-person). Safety was similar between formats (12 vs. 11 adverse events for online vs. in-person).
Conclusion: Supervised, in-person group resistance training can be feasibly adapted for live, online delivery and could help broaden approaches to exercise delivery in cancer survivors, including older adults.
Trial registration: The studies described in this commentary were registered on ClinicalTrials.gov on August 3, 2018 ( NCT03630354 ) and on October 30, 2018 ( NCT03741335 ).
Keywords: COVID-19; Cancer survivor; Clinical trial; Exercise.
【저자키워드】 COVID-19, exercise, clinical trial, Cancer survivor, 【초록키워드】 Randomized controlled trial, exercise, Efficacy, Breast cancer, Safety, feasibility, adherence, COVID-19 pandemic, resistance exercise, Cancer, Intervention, adverse events, improvement, Adults, Survivors, clinical, adverse event, age, Prostate cancer, group, Older, online delivery, help, Registered, participant, preliminary evidence, survivor, Resistance training, approach, described, participated, transitioned, 【제목키워드】 Cancer, reached,