Abstract
Objective: The characteristics and outcomes of patients undergoing vascular surgery hospitalised and managed in Lombardy are described with a comparison of patients tested positive for COVID-19 (CV19-pos) vs. those tested negative (CV19-neg).
Methods: This was a multicentre, retrospective, observational cohort study which involved all vascular surgery services in Lombardy, Northern Italy. Data were retrospectively merged into a combined dataset covering the nine weeks of the Italian COVID-19 pandemic phase 1 (8 March 2020 to 3 May 2020). The primary outcome was freedom from in hospital death, secondary outcomes were re-thrombosis rate after peripheral revascularisation, and freedom from post-operative complication.
Results: Among 674 patients managed during the outbreak, 659 (97.8%) were included in the final analysis: 121 (18.4%) were CV19-pos. CV19-pos status was associated with a higher rate of complications (OR 4.5; p < .001, 95% CI 2.64 – 7.84), and a higher rate of re-thrombosis after peripheral arterial revascularisation (OR 2.2; p = .004, 95% CI 1.29 – 3.88). In hospital mortality was higher in CV19-pos patients (24.8% vs. 5.6%; OR 5.4, p < .001;95% CI 2.86 – 8.92). Binary logistic regression analysis identified CV19-pos status (OR 7.6; p < .001, 95% CI 3.75 – 15.28) and age > 80 years (OR 3.2; p = .001, 95% CI 1.61 – 6.57) to be predictors of in hospital death.
Conclusion: In this experience of the vascular surgery group of Lombardy, COVID-19 infection was a marker of poor outcomes in terms of mortality and post-operative complications for patients undergoing vascular surgery treatments.
Keywords: COVID-19; acute limb ischaemia; vascular surgery activities.
【저자키워드】 COVID-19, acute limb ischaemia, vascular surgery activities., 【초록키워드】 Mortality, COVID-19 pandemic, hospital, outcome, Italy, Characteristics, COVID-19 infection, outbreak, Patient, death, Complication, age, multicentre, dataset, predictor, marker, retrospective, Analysis, lombardy, Binary logistic regression, Observational cohort study, Vascular, Primary outcome, 95% CI, activities, secondary outcome, Final, positive, hospitalised, Italian, limb, tested, described, involved, nine, 【제목키워드】 survey, surgery, Italy, lombardy, Regional,