Infection with non-typhoidal Salmonellae usually causes a self-limiting dysenteric illness. Several factors are known to increase the propensity to invasive disease–with its related sequelae. We present four previously healthy patients who had none of the recognised risk factors but developed Salmonella infection with a severe and protracted illness. Common to each of these patients was the pre-hospital oral administration of anti-diarrhoeal drugs.
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