The IgG and IgM immunoglobulins were fractionated from pooled sera of typhoid patients and typhoid carriers and the agglutinin titres and weights of Vi and O antibodies in these immunoglobulin fractions determined. The O antigen particles were more effectively agglutinated than the Vi antigen particles by their corresponding antibodies of the IgM class. There was no such difference between IgG class Vi and O antibodies. Similar behaviour was found on indirect estimation of the agglutination capacity of the IgG and IgM class Vi and O antibodies in the sera of individual typhoid patients or carriers. The significance of such differential agglutinating capacity of the Vi and O antibodies of the IgM class is discussed.
DIFFERENTIAL AGGLUTINATION OF PARTICULATE Vi AND O ANTIGENS BY THE IgM AND IgG CLASS ANTIBODIES
입자 Vi 및 O 항원의 차등 응집 반응에 대한 IgM 및 IgG 클래스 항체
[Category] 살모넬라증,
[Article Type] journal-article
[Source] pubmed
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