When rats are sub-lethally infected with S. entertidis by the intravenous route, there is a period of at least 14 days in which peritoneal exudate cells are unable to migrate from capillary tubes on to glass surfaces; thereafter they migrate as do macrophages from normal animals. The migration of peritoneal cells from rats infected 18-21 days previously is inhibited by lipopolysaccharide (LPS) prepared from homologous and heterologous strains of Salmonella. The apparent non-specificity of LPS activity in the macrophage migration inhibition test has been resolved by demonstrating that lipid A, containing less than 0.01% protein amino acids, is also capable of eliciting this test of cell-mediated immunity.
SALMONELLA ENTERITIDIS INFECTION IN RATS: ANTIGENS INVOLVED IN CELL‐MEDIATED IMMUNITY
쥐에서의 살모넬라 엔테리티디스 감염: 세포 매개 면역에 관여하는 항원들
[Category] 살모넬라증,
[Article Type] journal-article
[Source] pubmed
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