Abstract
Introduction: The COVID-19 pandemic has led to changes in NHS surgical service provision, including reduced elective surgical and endoscopic activity, with only essential emergency surgery being undertaken. This, combined with the government-imposed lockdown, may have impacted on patient attendance, severity of surgical disease, and outcomes. The aim of this study was to investigate a possible ‘lockdown’ effect on the volume and severity of surgical admissions and their outcomes.
Methods: Two separate cohorts of adult emergency general surgery inpatient admissions 30 days immediately before (February 16, 2020 to March 15, 2020), and after UK government advice (March 16, 2020 to April 15, 2020). Data were collected relating to patient characteristics, severity of disease, clinical outcomes, and compared between these groups.
Results: Following lockdown, a significant reduction in median daily admissions from 7 to 3 per day (p < 0.001) was observed. Post-lockdown patients were significantly older, frailer with higher inflammatory indices and rates of acute kidney injury, and also were significantly more likely to present with gastrointestinal cancer, obstruction, and perforation. Patients had significantly higher rates of Clavien-Dindo Grade ≥3 complications (p = 0.001), all cause 30-day mortality (8.5% vs. 2.9%, p = 0.028), but no significant difference was observed in operative 30-day mortality.
Conclusion: There appears to be a “lockdown” effect on general surgical admissions with a profound impact; fewer surgical admissions, more acutely unwell surgical patients, and an increase in all cause 30-day mortality. Patients should be advised to present promptly with gastrointestinal symptoms, and this should be reinforced for future lockdowns during the pandemic.
Keywords: COVID-19; Emergency surgery; Lockdown effect; Severity; Volume.
【저자키워드】 COVID-19, severity, Emergency surgery, Lockdown effect, Volume, 【초록키워드】 pandemic, lockdown, COVID-19 pandemic, Cancer, Acute kidney injury, surgical, clinical outcomes, outcomes, Cohort, Characteristics, Patient, Complication, Severity of disease, disease, Admission, patients, 30-Day mortality, gastrointestinal symptoms, Inflammatory, Emergency, GRADE, Volume, Admissions, NHS, Older, no significant difference, inpatient admission, operative, UK Government, collected, significantly more, significantly, reduced, median, per day, appear, changes in, increase in, significantly higher, groups, reduction in, impacted, 【제목키워드】 Admission, Volume, Observational cohort study, evaluate,