Abstract
Objectives: To report the outcome of patients with end stage kidney disease (ESKD) who were diagnosed with COVID-19 at a large community hospital in Eastern Saudi Arabia.
Methods: A single center, prospective observational study at Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia. Patients with ESKD who were maintained on dialysis and developed COVID-19 between June 15, 2020 and October 31, 2021 were enrolled.
Results: In total, 30 patients with ESKD were diagnosed with severe acute respiratory syndrome coronavirus 2 infection. Twenty two (73%) patients developed the disease prior to COVID-19 vaccine rollout. The median age of the cohort was 63 (55-75) years. Most patients were diabetic (73%), hypertensive (97%) and had a median body mass index of 28 kg/m 2 . Twenty seven (90%) patients required admission, 16 (52%) patients developed pneumonia, and 5 (17%) patients required mechanical ventilation. Patients who developed pneumonia were older, and the majority had diabetes mellitus and coronary artery disease. Five patients died with a total mortality of 17%.
Conclusion: Patients with ESKD who developed COVID-19 had a poor outcome with high mortality compared to the general population. Presence of diabetes mellitus, coronary artery disease and older age were associated with a higher risk of severe disease. There was a sharp decline in the number of positive cases following implementation of the vaccination program.
Keywords: COVID-19; SARS-CoV-2 infection; end stage kidney disease.
【저자키워드】 COVID-19, SARS-COV-2 infection, end stage kidney disease., 【초록키워드】 SARS-CoV-2, coronavirus, COVID-19 vaccine, vaccination, mechanical ventilation, Pneumonia, prospective observational study, hospital, Infection, Diabetes Mellitus, outcome, Saudi Arabia, dialysis, Coronary artery disease, Cohort, body mass index, implementation, Patient, Older age, Kidney disease, Community, General population, Admission, severe disease, Diabetic, acute respiratory syndrome, Older, higher risk, median age, hypertensive, high mortality, single center, total mortality, positive, Seven, Dhahran, enrolled, diagnosed, the disease, required, Most patient, median, majority, diagnosed with COVID-19, Johns Hopkin, patients died, Presence, 【제목키워드】 hospital, Prospective Study, Saudi Arabia, Kidney disease, Community, COVID-19 in patient,