The accuracy of the latex particle agglutination test (LPAT) was assessed in blood stained cerebrospinal fluid (CSF) specimens from 166 paediatric patients, aged from three months to 13 years. A commercial LPAT kit was used to detect Haemophilus influenzae type b, Streptococcus pneumoniae, and Neisseria meningitidis A, B, and C soluble antigens. Culture of CSF specimens was used as the standard and all laboratory procedures were performed blind. The mean CSF erythrocyte count was 66,406 cells/mm3 in the cases and 11,560 cells/mm3 in the controls. The sensitivity and the specificity of LPAT were 83.8 and 94.0%, respectively, suggesting that LPAT is a useful diagnostic tool even in blood stained CSF specimens.
Blood stained cerebrospinal fluid responsible for false positive reactions of latex particle agglutination tests.
혈액이 오염된 뇌척수액은 라텍스 입자 응집 검사에서 잘못된 양성 반응을 유발합니다.
[Category] 폐렴구균 감염증,
[Article Type] journal-article
[Source] pubmed
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