Abstract
Background and aims
To propose an integrative model for post-COVID symptoms by considering the absence/presence of previous symptomatology.
Methods
We searched different databases for original articles and reviews on post-COVID symptoms.
Results
The first consideration is to define which symptoms are of “new-onset” (symptoms never experienced by a patient before COVID-19 and experienced the first time after) and which symptoms are “exacerbated” (symptoms experienced by a patient prior to COVID-19 but aggravated later) after infection. The second consideration includes defining “persistent” (symptoms experienced at the acute phase and continuing after without remission period) and “delayed-onset” (symptoms not experienced at the acute phase of the infection but appearing after a “latency period”). This model integrates predisposing individual factors, biological factors associated to the severity of disease, hospitalization/treatment factors, and outbreak surrounding factors which may promote post-COVID.
Conclusion
Since current literature on post-COVID is heterogeneous, this integrative model could help to a better characterization of long-COVID.
【저자키워드】 COVID-19, classification, Symptoms, Long COVID, persistent, Definition, 【초록키워드】 Infection, Symptom, database, outbreak, Patient, Factors, long-COVID, Severity of disease, Factor, acute phase, help, heterogeneous, article, Result, include, searched, promote, to define, 【제목키워드】 Symptom,