Abstract
Introduction
Coronavirus disease 2019 (COVID-19) is caused by a newly identified strain of the coronavirus family that has been shown to affect the hemoglobin beta chain, the same chain that has sickle cell disease (SCD) mutation. This study was undertaken to see if COVID-19 infection increased disease severity in patients with SCD.
Methods
Mass screening of the Bahraini population was undertaken between February and April 2020.
Results
A total of 38,092 Bahraini people were tested for COVID-19 during this period; 378 (1%) were SCD patients. Six patients with SCD had COVID-19 (1.6%): three remained asymptomatic, two had mild symptoms and one required oxygen therapy. The SCD patients had a similar average length of stay when compared with non-SCD COVID-19 patients (10.7 days).
Conclusion
The infection rate, clinical course and viral clearance seen for the SCD patients with COVID-19 were no different to those without SCD.
【저자키워드】 COVID-19, SARS-CoV-2, Sickle cell disease, 【초록키워드】 Coronavirus disease 2019, coronavirus, Mutation, disease severity, viral clearance, Clinical course, Mass screening, Asymptomatic, COVID-19 infection, Patient, Oxygen therapy, hemoglobin, infection rate, disease, patients, COVID-19 patient, Mild symptom, average, Affect, Cell, SCD, Result, shown, tested, caused, remained, required, patients with COVID-19, 【제목키워드】 disease, Bahrain, Cell,