Abstract
The second wave of the COVID-19 pandemic in India had brought with it a surge of ‘black fungus’ co-infection, which is a misnomer for mucormycosis. The present case illustrates the ‘real black fungus’ infection in a 50-year old male patient with COVID-19 pneumonia, who otherwise had no significant previous medical history. He was admitted on day 8 of COVID-19 illness and was intubated due to persistently low oxygen saturation. Blood cultures were positive for flask-shaped dematiaceous budding yeasts with pseudohyphae formation, which grew as brown-black fuzzy colonies on Sabouraud dextrose agar. The isolate was identified as Exophiala dermatitidis based on phenotypic characterization. Despite antifungal therapy with amphotericin B and itraconazole, the patient deteriorated rapidly and succumbed to acute respiratory distress syndrome and multiorgan failure. A review of reported cases of Exophiala dermatitidis fungemia over the last 5-years is discussed.
【저자키워드】 COVID-19, coronavirus, Malaysia, Antifungal, Dematiaceous, Mycosis, 【초록키워드】 Pneumonia, COVID-19 pandemic, India, Infection, oxygen saturation, Mucormycosis, male, Co-infection, second wave, yeast, acute respiratory distress, fungemia, Intubated, multiorgan failure, syndrome, COVID-19 illness, phenotypic, positive, colony, blood culture, patient with COVID-19, antifungal therapy, reported, the patient, had no, Exophiala, 【제목키워드】 fungemia, patient with COVID-19, Exophiala,