Abstract
Introduction
and importance: Systemic capillary leak syndrome (SCLS) and multisystem inflammatory syndrome in adults (MIS-A) are very rare multifactorial etiology disorders associated with COVID-19 infection. Both conditions are thought to be manifested by the inflammatory state induced by COVID-19 infection. Recurrent COVID-19-associated concomitant/successive manifestations of both disorders have not been reported yet.
Case presentation
We report a 38-year-old Asian gentleman who presented initially with fever, cough, shortness of breath, body aches, dizziness, and epigastric pain due to COVID-19 infection. A few days before this presentation, the same patient developed multisystem inflammatory syndrome in adults (MIS-A). Later, based on clinical and laboratory investigations, he was diagnosed with new-onset systemic capillary leak syndrome (SCLS). Despite resuscitative measures, the patient passed away.
Clinical discussion
The increased risk of inflammatory complications associated with COVID-19 infection is an emerging concern. Our case report signifies the importance of COVID-19 awareness in less educated and underserved areas with fewer information resources. Rare and fatal manifestations should also be advertised and discussed with the general masses with equal emphasis.
Conclusion
This case signifies the importance of understanding the pathophysiology of new-onset systemic capillary leak syndrome in a patient with recurrent COVID-19 infection and utilizing clinical knowledge and decision-making to manage such rare and complex disorders.
【저자키워드】 COVID-19, Infection, Case report, MIS-A, Capillary leak, SCLS, Multisystem inflammation, 【초록키워드】 knowledge, cough, Laboratory, Measures, COVID-19 infection, pathophysiology, clinical, Fever, Patient, Pain, Recurrent, etiology, information, Inflammatory, inflammatory state, manifestation, Dizziness, systemic, Shortness of breath, Asian, increased risk, syndrome, disorder, body aches, complex disorders, multifactorial, resources, thought, reported, the patient, diagnosed, condition, less, manifested, capillary leak syndrome, inflammatory complication, with COVID-19, 【제목키워드】 Patient, Inflammatory, literature review, syndrome, capillary leak syndrome,