Abstract
The novel coronavirus infection (COVID-19) caused by the SARS-CoV-2 virus is a relatively recent infection that has resulted in a global pandemic, appearing first at the end of 2019. While initially presenting as a predominantly respiratory disease, with a classical picture of fever, dry cough, dyspnea and, in some cases anosmia and ageusia, recent cases have shown increasingly atypical and more systemic manifestation of the disease. A precise understanding of the extent and pathophysiology of COVID-19 remains underway to this day, particularly concerning its behavior in the pediatric population. Moreover, there has been an increasing number of COVID-19 reports with neurological complications and manifestations, prompting inquiry into neuroinvasion. Postulations include indirect invasion through a surge of inflammatory mediators “cytokine storm” and subsequent widespread endothelial injury; and direct neural tropism. We report the case of a previously healthy 12-year-old male presenting with acute right-sided hemiparesis, new-onset seizures and a generalized petechial rash. Laboratory tests revealed elevated inflammatory markers and radiological investigations confirmed an evolving left middle cerebral artery (MCA) infarct and large vessel vasculitis. Testing for SARS-CoV-2 infection was positive.
【저자키워드】 COVID-19, COVID-19 complications, Vasculitis, COVID-19 vasculitis, Pediatric neuroradiology, NEURORADIOLOGY, 【초록키워드】 SARS-COV-2 infection, pediatric, Infection, Anosmia, global pandemic, Testing, Ageusia, pathophysiology, Fever, Dyspnea, Respiratory disease, male, Manifestations, Inflammatory marker, Novel coronavirus infection, Rash, Seizure, Atypical, Invasion, Neurological complication, Laboratory test, endothelial, dry cough, positive, while, inquiry, widespread, radiological, inflammatory mediator, shown, classical, caused, include, healthy, subsequent, the disease, elevated, presenting, concerning, increasingly, “cytokine storm”, large vessel, the SARS-CoV-2 virus, 【제목키워드】 pediatric, Case report, Complication, Vascular,