Abstract
Objective
To evaluate the efficacy of mixed oral prednisolone and intratympanic dexamethasone (ITID) injection in labyrinthitis, due to COVID 19.
Methods
Seventy-five post-COVID-19 labyrinthitis patients were included. Those patients were treated with systemic oral prednisolone for two weeks and ITID. Patients who refuse ITID were ordered to continue oral prednisolone treatment. Assessment of outcome and audiometry for hearing evaluation was done 1, 2 and 4 weeks as well as 3 months post-treatment.
Results
Patients in oral steroid only group were 26 patients, while patients in oral steroid and ITID group were 49 patients. In oral steroid group; 11/26 patients showed complete recovery, 3/26 had partial recovery and 12/26 not recovered. In other group; 38/46 patients had complete recovery, 6 had partial recovery and 5/49 patients not recovered.
Conclusion
Combined systemic corticosteroid with ITID showed a marked improvement of post-COVID vestibular disorder and hearing loss than only using oral corticosteroid therapy.
【저자키워드】 COVID-19, Dexamethasone, hearing loss, Labyrinthitis, 【초록키워드】 Treatment, Efficacy, outcome, COVID 19, Patient, assessment, patients, Prednisolone, complete recovery, injection, corticosteroid therapy, objective, Combined, Result, evaluate, treated, was done, oral steroid, systemic corticosteroid, vestibular disorder, 【제목키워드】 management, disease, injection, with COVID-19,