Abstract
Background
Recent studies have focused on the incidence rate and pattern of meningoencephalitis in the coronavirus disease 2019 (COVID-19).
Aim
This study aims to shed more light on the CSF pattern and clinical characteristics of meningoencephalitis COVID-19 patients in Zanjan, Iran.
Methods
Nine cases of laboratory and imaging confirmed COVID-19 were admitted to Valiasr Hospitals in Zanjan, Iran. Data were collected from May 20, 2020 to June 20, 2020.
Results
All the nine patients had positive RT-PCR COVID-19 and Pulmonary involvement who underwent Lumbar puncture and analysis, but despite neurological symptoms, the RT-PCR of CSF for COVID-19 was negative.
Conclusion
Although we did not have any cases of positive RT-PCR for COVID-19 in lumbar puncture specimens, the justification of neurological symptoms in patients can be the transient presence of the virus in the CSF, and inflammation or autoimmune response caused by the virus, so more studies are needed to determine the cause of neurogenic symptoms.
【저자키워드】 COVID-19, Reverse transcriptase polymerase chain reaction, meningoencephalitis, 【초록키워드】 coronavirus disease, Inflammation, Clinical characteristics, RT-PCR, virus, pulmonary, Symptoms, Laboratory, Iran, Patient, incidence rate, Neurological symptoms, specimens, CSF, positive RT-PCR, Analysis, Autoimmune response, COVID-19 patient, lumbar, recent, Neurological symptom, Result, collected, caused, nine, determine, 【제목키워드】 Biomarker, CSF, case sery,