Abstract
Background
Patients with comorbidities have an increased risk for severe coronavirus disease (COVID-19) symptoms, including abnormal inflammation. Chest X-rays and C-reactive protein (CRP) level are frequently used to evaluate the severity of inflammation. The aim of this study was to investigate the correlation between comorbidities, chest X-ray findings, and CRP level in patients with COVID-19.
Materials and methods
This was a cross-sectional, analytic, observational study performed using a quantitative approach. The study population included in patients with confirmed COVID-19. Secondary data from the medical records of the patients were analysed to determine the correlations between comorbidities, chest X-rays, and CRP level.
Results
The data of 167 patients (87 [52.1%] females and 80 [47.9%] males) were evaluated. Regarding comorbidities, 86 (51.5%) patients had hypertension, 66 (39.5%) had diabetes mellitus, and 17 (10.2%) had dyspepsia. Chest X-rays showed that 144 (86.2%) patients had pneumonia, whereas 23 (13.8%) did not. A total of 143 (85.6%) patients showed increased CRP levels, whereas 24 (14.4%) did not show any increase. Patients who showed pneumonia on chest X-rays tended to have increased CRP levels. The results also showed that chest X-ray findings were correlated with CRP level. Diabetes mellitus and hypertension were significantly correlated with CRP level (p = 0.05), whereas dyspepsia did not show a significant relationship with CRP level (p > 0.05). Patients with hypertension had a 2.709-fold risk of having increased CRP level compared with patients without hypertension. Patients with pneumonia had a 2.953-fold increased risk for increased CRP level compared to those without pneumonia.
Conclusion
Hypertension and diabetes mellitus are significantly correlated with CRP level. Chest X-ray finding is also significantly correlated with CRP level.
【저자키워드】 COVID-19, Comorbidity, C-reactive protein, chest X-ray, 【초록키워드】 Inflammation, Pneumonia, cross-sectional, severity, Comorbidities, Diabetes Mellitus, risk, hypertension, Symptoms, X-ray, Chest, female, Patient, correlation, Quantitative, C-reactive protein (CRP, medical record, increased risk, study population, severe coronavirus disease, CRP levels, material, CRP level, approach, secondary, males, dyspepsia, Result, performed, significantly, the patient, evaluated, analysed, determine, correlated, patients with COVID-19, used to evaluate, 【제목키워드】 Comorbidities, Chest, protein level, patients with COVID-19,