Abstract
Rapid detection of human coronavirus disease 2019, termed as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) or COVID-19 infection, is urgently needed for containment strategy owing to its unprecedented spreading. Novel biosensors can be deployed in remote clinical settings without central facilities for infection screening. Electrochemical biosensors serve as analytical tools for rapid detection of viral structure proteins, mainly spike (S) and nucleocapsid (N) proteins, human immune responses, reactive oxygen species, viral ribonucleic acid, polymerase chain reaction by-products, and other potential biomarkers. The development of point-of-care testing devices is challenging due to the requirement of extensive validation, a time-consuming and expensive step. Together with specific biorecognition molecules, nanomaterial-based biosensors have emerged for the fast detection of early viral infections.
【저자키워드】 antibodies, SARS-CoV-2, point of care, Diagnosis, Viral proteins, biosensor, Electrochemistry, 【초록키워드】 coronavirus disease, coronavirus, Infection, Proteins, viral infections, point-of-care, COVID-19 infection, nucleocapsid, immune responses, Rapid, novel, reactive oxygen species, acute respiratory syndrome, viral ribonucleic acid, potential biomarkers, clinical setting, polymerase chain, time-consuming, 【제목키워드】 COVID-19,