Tetanus is a life-threatening but vaccine-preventable disease caused by the toxin of the bacterium Clostridium tetani and is characterized by muscle spasms and autonomic nervous system dysfunction. It is prevented through vaccination with tetanus toxoid, but because the causative agent is widespread in the environment, eradication is impossible. Therefore, efforts to reduce incidence are aimed at reaching elimination, rather than eradication. This article reviews the pathogenesis, clinical manifestation and treatment of tetanus, and summarizes all recommendations from CDC’s Advisory Committee on Immunization Practices (ACIP) regarding prevention and control of tetanus in the United States.
All Keywords
【저자키워드】 Tetanus, tetanus vaccine, Tetanus immunoglobulin, tetanus prophylaxis,
【저자키워드】 Tetanus, tetanus vaccine, Tetanus immunoglobulin, tetanus prophylaxis,