Summary
COVID-19, caused by SARS-CoV-2, is characterised by a broad spectrum of symptom severity that requires varying amounts of care according to the different stages of the disease. Intervening at the onset of mild to moderate COVID-19 symptoms in the outpatient setting would provide the opportunity to prevent progression to a more severe illness and long-term complications. As early disease symptoms variably reflect an underlying excessive inflammatory response to the viral infection, the use of anti-inflammatory drugs, especially non-steroidal anti-inflammatory drugs (NSAIDs), in the initial outpatient stage of COVID-19 seems to be a valuable therapeutic strategy. A few observational studies have tested NSAIDs (especially relatively selective COX-2 inhibitors), often as part of multipharmacological protocols, for early outpatient treatment of COVID-19. The findings from these studies are promising and point to a crucial role of NSAIDs for the at-home management of people with initial COVID-19 symptoms.
【초록키워드】 COVID-19, Treatment, SARS-CoV-2, viral infection, Anti-inflammatory drugs, Symptom, progression, inhibitors, observational study, Moderate COVID-19, excessive inflammatory response, NSAIDS, management, Mild, complications, COVID-19 symptoms, Care, therapeutic strategy, NSAID, protocols, non-steroidal anti-inflammatory drug, Stage, symptom severity, selective, Prevent, initial, tested, caused, the disease, disease symptom, 【제목키워드】 Treatment, anti-inflammatory agent, home,