In the DECODE project, data were collected from 3,114 surveys filled by symptomatic patients RT-qPCR tested for SARS-CoV-2 in a single university centre in March-September 2020. The population demonstrated balanced sex and age with 759 SARS-CoV-2( +) patients. The most discriminative symptoms in SARS-CoV-2( +) patients at early infection stage were loss of taste/smell (OR = 3.33, p < 0.0001), body temperature above 38℃ (OR = 1.67, p < 0.0001), muscle aches (OR = 1.30, p = 0.0242), headache (OR = 1.27, p = 0.0405), cough (OR = 1.26, p = 0.0477). Dyspnea was more often reported among SARS-CoV-2(-) (OR = 0.55, p < 0.0001). Cough and dyspnea were 3.5 times more frequent among SARS-CoV-2(-) (OR = 0.28, p < 0.0001). Co-occurrence of cough, muscle aches, headache, loss of taste/smell (OR = 4.72, p = 0.0015) appeared significant, although co-occurrence of two symptoms only, cough and loss of smell or taste, means OR = 2.49 ( p < 0.0001). Temperature > 38℃ with cough was most frequent in men (20%), while loss of taste/smell with cough in women (17%). For younger people, taste/smell impairment is sufficient to characterise infection, whereas in older patients co-occurrence of fever and cough is necessary. The presented study objectifies the single symptoms and interactions significance in COVID-19 diagnoses and demonstrates diverse symptomatology in patient groups.
【저자키워드】 Risk factors, Epidemiology, Respiratory signs and symptoms, 【초록키워드】 COVID-19, SARS-CoV-2, Infection, Sex, Symptom, cough, headache, RT-qPCR, older patient, Symptomatic patients, qPCR, Fever, Dyspnea, Patient, age, temperature, women, Taste, patients, body temperature, diagnose, Interaction, older patients, early infection, Loss of Smell, muscle ache, patient groups, younger people, muscle aches, impairment, loss of smell or taste, men, tested, collected, reported, demonstrated, co-occurrence, symptomatic patient, 【제목키워드】 SARS-CoV-2, respiratory tract, pilot study,