Abstract
Objective
To evaluate the factors associated with the intention to participate in COVID-19 vaccine clinical trials in the Peruvian population.
Methods
Cross-sectional study and secondary analysis of a database that involved Peruvian population during September 2020. The Poisson regression model was used to estimate the associated factors.
Results
Data from 3231 individuals were analyzed, 44.1% of whom intended to participate in COVID-19 vaccine clinical trials. Factors associated with the outcome were being male (RPa: 1.25; 95% CI: 1.15–1.35), being from the highlands region (RPa: 1.18; 95% CI: 1.09–1.28) or jungle (RPa: 1.30; 95% CI: 1.15–1.47), having a relative that is a healthcare professional (PRa: 1.16; 95% CI: 1.06–1.28), using a medical source of information (PRa: 1.28; 95% CI: 1.17–1.41), and trusting in the possible effectiveness of vaccines (PRa: 1.40; 95% CI: 1.29–1.51). The main reason for not participating in the trial was the possibility of developing side effects (69.80%).
Conclusion
There is an urgent need to generate a perception of safety in COVID-19 vaccine clinical trials, to increase the population’s intention to participate in these studies, and to provide evidence-based information about the vaccine.
【저자키워드】 COVID-19, Vaccine, coronavirus, clinical trial, Associated factors, Intention to participate, 【초록키워드】 COVID-19 vaccine, Trial, clinical trials, outcome, database, cross-sectional study, male, Effectiveness, Factors, Intention, information, Healthcare professional, Analysis, Factor, Side effect, individual, Poisson regression model, objective, Result, analyzed, was used, evaluate, involved, generate, the vaccine, 【제목키워드】 COVID-19 vaccine, cross-sectional, Intention, Factor,