We describe here changes in the bacterial causes of pleural empyema before and after implementation of the 13-valent pneumococcal conjugate vaccine (PCV13) program in France (2009-2017). For 220 (39.3%) of 560 children, a bacterial cause was found. The frequency of pneumococcal infection decreased during the study from 79.1% in 2009 to 36.4% in 2017 (P < .001). Group A streptococcus is now the leading cause of documented empyema (45.5%).
All Keywords
【저자키워드】 children, bacterial pneumonia, pleural effusion, Empyema, PCV13,
【저자키워드】 children, bacterial pneumonia, pleural effusion, Empyema, PCV13,