Abstract
While the degree of COVID-19 vaccine accessibility and uptake varies at both national and global levels, increasing vaccination coverage raises questions regarding the standard of prevention that ought to apply to different settings where COVID-19 vaccine trials are hosted. A WHO Expert Group has developed guidance on the ethical implications of conducting placebo-controlled trials in the context of expanding global COVID-19 vaccine coverage. The guidance also considers alternative trial designs to placebo controlled trials in the context of prototype vaccines, modified vaccines, and next generation vaccines.
All Keywords
【저자키워드】 Research Ethics, Standard of care, Placebo-controlled trials, Standard of prevention, Trial designs, 【초록키워드】 COVID-19 vaccine, vaccination, Trial, Vaccines, Coverage, placebo-controlled trial, WHO, group, Guidance, placebo controlled trial, National, while, next generation vaccines, implication, expert, raise, question, COVID-19 vaccine trial, 【제목키워드】 COVID-19 vaccine, Trial, WHO, Guidance,
【저자키워드】 Research Ethics, Standard of care, Placebo-controlled trials, Standard of prevention, Trial designs, 【초록키워드】 COVID-19 vaccine, vaccination, Trial, Vaccines, Coverage, placebo-controlled trial, WHO, group, Guidance, placebo controlled trial, National, while, next generation vaccines, implication, expert, raise, question, COVID-19 vaccine trial, 【제목키워드】 COVID-19 vaccine, Trial, WHO, Guidance,