A hypothesis about the role of fetal hemoglobin in COVID-19

Published on
Journal: Medical Hypotheses
[저자] Ehsan Sotoudeh, Houman Sotoudeh
[Category] 임상,
[DOI] 10.1016/j.mehy.2020.109994    
[Article Type] Research article
[Source] Sciencedirect

Abstract
COVID-19 infection is less common in children (with higher fetal hemoglobin levels). In our preliminary study, we also observed a low prevalence and fatality of COVID-19 in countries with high rate of hemoglobinopathy carries. Given these two facts, the hemoglobin structure can play a role in the physiopathology of COVID-19 disease. Several drugs are known to increase fetal hemoglobin in adults. Adding these drugs to COVID-19 clinical trials may improve the patients’ outcomes.

All Keywords
【초록키워드】 COVID-19, clinical trial, children, drug, COVID-19 disease, Prevalence, outcomes, Adults, COVID-19 infection, hemoglobin, fatality, Hemoglobinopathy, country, IMPROVE, less, fetal, Adding, 【제목키워드】 COVID-19, hemoglobin, Hypothesis, fetal,