Abstract
Objectives
To identify potential predictors of COVID-19 vaccine hesitancy (C19-VH) in adults with immune-mediated inflammatory diseases (IMID).
Methods
A total of 1000 IMID patients were enrolled in this web-based cross-sectional study. A standardised and self-administered survey was designed by members of the Brazilian Society of Rheumatology Steering Committee for Infectious and Endemic diseases and distributed to IMID patients spread across Brazil.
Results
Of the 908 (90.8%) respondents eligible for analysis, 744 (81.9%) were willing to get vaccinated against COVID-19. In our multivariable logistic regression model, concurrent malignancy, fibromyalgia, hydroxychloroquine use, and recent corticosteroid pulse therapy were independently associated with higher odds of C19-VH. The short duration of COVID-19 vaccine clinical trials was the main reason for C19-VH.
Conclusion
We identified novel characteristics potentially associated with C19-VH among adults with IMID. Greater awareness on the safety and efficacy of COVID-19 vaccines is needed for both IMID patients and attending physicians.
【저자키워드】 COVID-19, Vaccine hesitancy, Vaccine acceptance, Immune-mediated inflammatory diseases, 【초록키워드】 Brazil, Efficacy, COVID-19 vaccine, clinical trial, therapy, Hydroxychloroquine, cross-sectional, Spread, Characteristics, Patient, Physicians, predictor, Analysis, malignancy, Endemic disease, Society, multivariable logistic regression, short duration, Immune-mediated inflammatory disease, objective, steering committee, Result, enrolled, identify, corticosteroid pulse, eligible, higher odd, vaccinated against COVID-19, 【제목키워드】 Vaccine, Patient, Immune-mediated inflammatory disease, with COVID-19,