Abstract
About 10% of people infected by severe acute respiratory syndrome coronavirus 2 experience post COVID-19 disease. We analysed data from 968 adult patients (5350 person-months) with a confirmed infection enroled in the ComPaRe long COVID cohort, a disease prevalent prospective e-cohort of such patients in France. Day-by-day prevalence of post COVID-19 symptoms was determined from patients’ responses to the Long COVID Symptom Tool, a validated self-reported questionnaire assessing 53 symptoms. Among patients symptomatic after 2 months, 85% still reported symptoms one year after their symptom onset. Evolution of symptoms showed a decreasing prevalence over time for 27/53 symptoms (e.g., loss of taste/smell); a stable prevalence over time for 18/53 symptoms (e.g., dyspnoea), and an increasing prevalence over time for 8/53 symptoms (e.g., paraesthesia). The disease impact on patients’ lives began increasing 6 months after onset. Our results are of importance to understand the natural history of post COVID-19 disease.
【초록키워드】 coronavirus, Infection, Symptom, Symptoms, COVID-19 disease, COVID, Prevalence, Cohort, symptomatic, response, Patient, France, disease, Dyspnoea, COVID-19 symptom, symptom onset, acute respiratory syndrome, paraesthesia, prevalent, Long, analysed, was determined, reported symptom, validated self-reported questionnaire, 【제목키워드】 Symptom, COVID-19 disease, COVID,