Background Half of U.S. adults have received at least one dose of the COVID-19 vaccines produced by either Pfizer, Moderna, or Johnson and Johnson, which represents a major milestone in the ongoing pandemic. Given the emergency use authorizations for these vaccines, their side effects and safety were assessed over a compressed time period. Hence, ongoing monitoring for vaccine-related adverse events is imperative for a full understanding and delineation of their safety profile. Case presentation An 22-year-old Caucasian male presented to our hospital center complaining of pleuritic chest pain. Six months prior he had a mild case of COVID-19, but was otherwise healthy. He had received his first dose of the Moderna vaccine three days prior to developing symptoms. Laboratory analysis revealed a markedly elevated troponin and multiple imaging modalities during his hospitalization found evidence of wall motion abnormalities consistent with a diagnosis of perimyocarditis. He was started on aspirin and colchicine with marked improvement of his symptoms prior to discharge. Conclusions We present a case of perimyocarditis that was temporally related to COVID-19 mRNA vaccination in an young male with prior COVID-19 infection but otherwise healthy. Our case report highlights an albeit rare but important adverse event for clinicians to be aware of. It also suggests a possible mechanism for the development of myocardial injury in our patient. Supplementary Information The online version contains supplementary material available at 10.1186/s12872-021-02183-3.
【저자키워드】 COVID-19, Case report, ECG, Myopericarditis, Cardiac MRI, 【초록키워드】 Vaccine, COVID-19 vaccine, pandemic, Hospitalization, Vaccines, hospital, Diagnosis, Emergency use authorization, Symptoms, discharge, Pfizer, myocardial injury, COVID-19 infection, adverse event, male, Patient, Mild, Aspirin, Colchicine, mechanism, safety profile, Moderna, Evidence, Analysis, dose, chest pain, COVID-19 mRNA Vaccination, Side effect, supplementary material, clinician, first dose, abnormality, highlight, produced, healthy, elevated, imperative, pleuritic, symptoms prior, were assessed, 【제목키워드】 SARS-CoV-2, Vaccine, mRNA-1273, Moderna, first dose, healthy,