Objectives COVID-19 outbreak brings a challenge to healthcare systems. The sex, age, and cardiometabolic comorbidities have been considered risk factors for disease severity. To evaluate the association between risk factors with death as well the risk of death in hospitalized COVID-19 patients. Methods The present cross-sectional cohort study, includes hospitalized SARS-CoV-2 confirmed cases. Data analysis was performed using the National COVID-19 Cases Report Database. Pearson’s χ 2 test and odds ratios (95% CI) were calculated to determine the association between variables. Thereafter, risk of death was evaluated by Cox proportional hazards model. Results A total of 67 328 inpatients were included; mean age 55.29 years (±15.97). Of total, 42 164 (62.62%) were men, 6 349 (9.43%) were intubated, and 23 873 (35.46%) died. Male sex, age older than 60 years, and cardiometabolic comorbidities were associated with death. Hazard ratio for death in older intubated patients was lower than in non-intubated (HR 1.242, 95%CI, 1.167–1.322; P < 0.001) and (HR 2.128, 95%CI, 2.066–2.193; P < 0.001) respectively. Conclusions Tracheal intubation or not is the most important predictor for death in COVID-19 infected patients in this Mexican cohort. Already known risk factors for COVID-19 severity may become less relevant once patients require tracheal intubation.
【저자키워드】 COVID-19, SARS-CoV-2, Risk factors, death, tracheal intubation, 【초록키워드】 Hospitalized, cross-sectional, disease severity, COVID-19 severity, Non-intubated, Comorbidity, intubation, Sex, risk factor, cohort study, Cohort, COVID-19 outbreak, Patient, age, association, cardiometabolic, Analysis, Odds ratio, Healthcare systems, Inpatient, risk of death, Older, Intubated, hospitalized COVID-19 patients, 95%CI, 95% CI, confirmed cases, hazard, report, men, objective, Result, evaluate, died, include, evaluated, was performed, calculated, less, determine, infected patient, tracheal, Cox proportional hazard, death in COVID-19, intubated patient, variables, 【제목키워드】 Mortality, population-based cohort, hospitalized COVID-19,