Objectives: To present a single-centre experience on CT pulmonary angiography (CTPA) for the assessment of hospitalised COVID-19 patients with moderate-to-high risk of pulmonary thromboembolism (PTE). Methods: We analysed consecutive COVID-19 patients (RT-PCR confirmed) undergoing CTPA in March 2020 for PTE clinical suspicion. Clinical data were retrieved. Two experienced radiologists reviewed CTPAs to assess pulmonary parenchyma and vascular findings. Results: Among 34 patients who underwent CTPA, 26 had PTE (76%, 20 males, median age 61 years, interquartile range 54–70), 20/26 (77%) with comorbidities (mainly hypertension, 44%), and 8 (31%) subsequently dying. Eight PTE patients were under thromboprophylaxis with low-molecular-weight heparin, four PTE patients had lower-limbs deep vein thrombosis at ultrasound examination (performed in 33/34 patients). Bilateral PTE characterised 19/26 cases, with main branches involved in 10/26 cases. Twelve patients had a parenchymal involvement >75%, the predominant pneumonia pattern being consolidation in 10/26 patients, ground glass opacities in 9/26, crazy paving in 5/26, and both ground glass opacities and consolidation in 2/26. Conclusion: COVID-19 patients are prone to PTE. Advances in knowledge: PTE, potentially attributable to an underlying thrombophilic status, may be more frequent than expected in COVID-19 patients. Extension of prophylaxis and adaptation of diagnostic criteria should be considered.
【초록키워드】 thrombosis, Pneumonia, Comorbidity, risk, RT-PCR, hypertension, Prophylaxis, clinical, Patient, Thromboembolism, consolidation, patients, COVID-19 patients, Thromboprophylaxis, COVID-19 patient, CTPA, pulmonary angiography, Diagnostic Criteria, interquartile range, Ground glass opacity, Vascular, median age, clinical suspicion, advance, radiologist, pulmonary parenchyma, males, performed, involved, analysed, predominant, expected, Bilateral, hospitalised COVID-19 patient, parenchymal, retrieved, 【제목키워드】 Italy, moderate, Pulmonary thromboembolism, lombardy, high risk, well, hospitalised COVID-19 patient,