Background Covid-19 is defined by an association of multiple symptoms, including frequently reported olfactory and gustatory disorders. Objective The main purpose of this study was to analyze the prevalence of these neurosensory impairments in patients with Covid-19, and to assess short-term recovery. Methods We performed a multicenter case series study during the Covid-19 epidemic. All patients presenting a RT-PCR-confirmed SARS-CoV-2 infection were included, whether hospitalized or treated at home. To analyze the prevalence and features of olfactory and gustatory dysfunctions, a phone interview was conducted 5 days after the positive PCR result. The questionnaire was submitted again 10 days later to patients having reported olfactory and gustatory disorders, in order to assess their recovery. Results 115 patients were included in our study. 81 patients (70%) reported olfactory and gustatory disorders without nasal obstruction or rhinorrhea. These impairments were more frequently reported in the female population, young people, and house-bound patients with mild symptomatic forms. Short-term recovery assessed at Day 15 was complete for 64% of the patients, and incomplete in 33%. Median recovery time was 15 days (4–27 days) after olfactory or gustatory symptom onset. Conclusion Olfactory and gustatory dysfunctions related to Covid-19 are frequently reported and prevalent in mild symptomatic forms of the disease. Recovery in most cases seems rapid and complete.
【저자키워드】 COVID-19, SARS-CoV-2, Anosmia, recovery, Ageusia, olfactory disorders, Gustatory disorders, 【초록키워드】 Hospitalized, SARS-COV-2 infection, nasal, Symptoms, Prevalence, Epidemic, symptomatic, female, Patient, Mild, multicenter, questionnaire, patients, association, olfactory, dysfunction, symptom onset, Gustatory, disorders, disorder, rhinorrhea, impairment, forms, positive PCR result, Complete, objective, feature, prevalent, Result, defined, performed, reported, the disease, Day, form, conducted, case sery, treated, submitted, presenting, 【제목키워드】 multicenter study, Prospective,