Background Severe coronavirus disease-19 (COVID-19) presents with progressive dyspnea, which results from acute lung inflammatory edema leading to hypoxia. As with other infectious diseases that affect the respiratory tract, asthma has been cited as a potential risk factor for severe COVID-19. However, conflicting results have been published over the last few months and the putative association between these two diseases is still unproven. Methods Here, we systematically reviewed all reports on COVID-19 published since its emergence in December 2019 to June 30, 2020, looking into the description of asthma as a premorbid condition, which could indicate its potential involvement in disease progression. Results We found 372 articles describing the underlying diseases of 161,271 patients diagnosed with COVID-19. Asthma was reported as a premorbid condition in only 2623 patients accounting for 1.6% of all patients. Conclusions As the global prevalence of asthma is 4.4%, we conclude that either asthma is not a premorbid condition that contributes to the development of COVID-19 or clinicians and researchers are not accurately describing the premorbidities in COVID-19 patients.
【저자키워드】 SARS-CoV-2, coronavirus, lung, allergy, respiratory insufficiency, 【초록키워드】 COVID-19, Asthma, severe COVID-19, hypoxia, Infectious disease, underlying disease, Prevalence, Disease progression, Coronavirus disease-19, Dyspnea, Patient, edema, respiratory tract, disease, patients, COVID-19 patients, association, Inflammatory, potential risk, article, Affect, Result, reported, contribute, clinicians and researcher, diagnosed with COVID-19, premorbid, 【제목키워드】 systematic review,