Objective To test the feasibility and acceptability of a short-term reminder and incentives intervention in adolescents with low adherence to asthma medications. Methods Mixed-methods feasibility study in a tertiary care clinic. Adolescents recruited to a 24-week programme with three 8-weekly visits, receiving electronic reminders to prompt inhaled corticosteroid (ICS) inhalation through a mobile app coupled with electronic monitoring devices (EMD). From the second visit, monetary incentives based on adherence of ICS inhalation: £1 per dose, maximum £2 /day, up to £112/study, collected as gift cards at the third visit. End of study interviews and questionnaires assessing perceptions of asthma and ICS, analysed using the Perceptions and Practicalities Framework. Participants Adolescents (11–18 years) with documented low ICS adherence (<80% by EMD), and poor asthma control at the first clinic visit. Results 10 out of 12 adolescents approached were recruited (7 males, 3 females, 12–16 years). Eight participants provided adherence measures up to the fourth visits and received rewards. Mean study duration was 281 days, with 7/10 participants unable to attend their fourth visit due to COVID-19 lockdown. Only 3/10 participants managed to pair the app/EMD up to the fourth visit, which was associated with improved ICS adherence (from 0.51, SD 0.07 to 0.86, SD 0.05). Adherence did not change in adolescents unable to pair the app/EMD. The intervention was acceptable to participants and parents/guardians. Exit interviews showed that participants welcomed reminders and incentives, though expressed frustration with app/EMD technological difficulties. Participants stated the intervention helped through reminding ICS doses, promoting self-monitoring and increasing motivation to take inhalers. Conclusions An intervention using electronic reminders and incentives through an app coupled with an EMD was feasible and acceptable to adolescents with asthma. A pilot randomised controlled trial is warranted to better estimate the effect size on adherence, with improved technical support for the EMD.
【저자키워드】 Asthma, respiratory medicine (see thoracic medicine), paediatric thoracic medicine, 【초록키워드】 COVID-19, randomised controlled trial, feasibility, lockdown, adherence, Intervention, inhalers, Adolescent, Care, questionnaire, dose, Perception, framework, Support, exit, measure, participant, effect size, doses, females, objective, males, inhaled corticosteroid, asthma medications, Result, collected, recruited, provided, receiving, analysed, expressed, feasible, EMD, End, ICS, technological difficulties, 【제목키워드】 Treatment, feasibility, Inhaled, Care, IMPROVE,