The ability of erythrocytes to absorb Vi-antigen at optimal (Sopt) and minimal (Smin) sensitizing doses in 52 patients suffering from enteric fever and 61 healthy individuals was studied. Smin has been found to be independent of ABO phenotype of both ill and healthy individuals. At the same time Sopt is considerably reduced in patients having A blood group as compared to healthy individuals. Relationship between antigen binding rigidity with erythrocyte receptors and individual blood groups has been determined.
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