Millions of people are affected by COVID-19 since the last quarter of 2019. Treatment using hydroxychloroquine (HCQ) as monotherapy in combination with azithromycin (HCQ-AZ) were administered at several clinical centres to patients tested positive to the virus across continents. Therefore, it is of interest to document the molecular docking analysis data of azithromycin and hydroxychloroquine drug with the spike surface glycoprotein of novel COVID-19. Thus, we report the molecular modelling docking based structural binding features of HCQ-AZ with the spike surface glycoprotein of COVID-19 for further evaluation in this regard.
All Keywords
【저자키워드】 drugs, molecular docking, pharmacokinetics, structure activity relationship, binding pocket, 【초록키워드】 COVID-19, Hydroxychloroquine, docking, virus, Surface glycoprotein, Patient, HCQ, molecular, monotherapy, binding, Combination, molecular docking analysis, positive, Administered, feature, tested, affected, 【제목키워드】 SARS-CoV-2, Hydroxychloroquine, docking, Surface glycoprotein, Analysis,
【저자키워드】 drugs, molecular docking, pharmacokinetics, structure activity relationship, binding pocket, 【초록키워드】 COVID-19, Hydroxychloroquine, docking, virus, Surface glycoprotein, Patient, HCQ, molecular, monotherapy, binding, Combination, molecular docking analysis, positive, Administered, feature, tested, affected, 【제목키워드】 SARS-CoV-2, Hydroxychloroquine, docking, Surface glycoprotein, Analysis,