The majority of people infected with SARS-CoV-2 fully recovered within a few weeks. However, a considerable number of patients of different ages still suffer from long-lasting problems similar to the multi-organ damage in its acute phase of infection, or experience symptoms continuously for a longer term after the recovery. The severity of the primary infection seems not to be associated with the possibility and severity of long-term symptoms. Various unresolved symptoms have been reported in COVID-19 survivors months after hospital discharge. Long COVID-19 Syndrome refers to survivors 4 months after initial symptoms onset. It is important to understand the systemic effects of Long COVID-19 Syndrome, its presentations, and the need for rehabilitations to restore functional recovery in survivors. Government, healthcare workers, and survivor groups should collaborate to establish a self-sustaining system to facilitate follow-up and rehabilitations, with prioritization of resources to more severely Long COVID-19 Syndrome survivors. This review looks into the systemic effects of Long COVID-19 Syndrome in various aspects: respiratory, cardiovascular, hematological, renal, gastrointestinal, neurological, and metabolic effects of Long COVID-19 Syndromes. Recommendations for follow-up and rehabilitations details have been explored to cope with the tremendous Long COVID-19 Syndrome patients.
【저자키워드】 recovery, Long COVID-19 syndrome, Post COVID-19 syndrome, rehabilitations, 【초록키워드】 COVID-19, severity, Infection, rehabilitation, Symptom, Symptoms, Survivors, healthcare, Patient, age, Follow-up, group, resource, patients, Primary infection, neurological, Multi-organ damage, initial symptom, acute phase, hospital discharge, problem, hematological, renal, survivor, Long, reported, facilitate, functional, majority, long-lasting, infected with SARS-CoV-2, metabolic effect, systemic effect, 【제목키워드】 COVID-19, review, plan, Effect, System, Long, Comprehensive,