Abstract Objectives: Hypertension is thought to be a contributor to mortality in coronavirus disease 2019 patients; however, limited clinical data on the outcomes of COVID-19 in patients with hypertension are available. Methods: This study was designed to confirm whether hypertension affects the outcomes of COVID-19. Results: A total of 983 patients with COVID-19 (female, 48%; male, 52%) were enrolled. Significantly higher odds of 60-day mortality ( p = .017) were observed in the hypertensive group. In the hypertensive group, even after adjustment in multivariate analysis, the subgroup of patients 70 years old and older had higher 28-day mortality and total 60-day mortality rates than the other age subgroups (both p < .05). A total of 297 (89%) COVID-19 patients with hypertension survived, and 35 (11%) died. In addition, compared with hypertensive patients who survived COVID-19, non-survivors had more pre-existing conditions, including cardiovascular diseases and stroke, higher blood pressure on admission, more severe inflammation, and more liver and kidney damage. Conclusion: Hypertension does not affect the outcome of COVID-19, which is different than the conclusions drawn in other studies. However, the 28-day mortality and total 60-day mortality rates of hypertensive patients (age ≥ 70) with COVID-19 were significantly elevated, and compared with the group of survivors, non-surviving COVID-19 patients with hypertension were older, had more basic diseases and had a more severe clinical condition.
【저자키워드】 COVID-19, Mortality, Clinical characteristics, hypertension, age, 【초록키워드】 coronavirus disease, stroke, 28-day mortality, cardiovascular disease, outcome, Survivors, male, female, mortality rate, disease, Admission, liver, Analysis, blood pressure, COVID-19 patient, subgroup, Older, Clinical data, hypertensive, clinical condition, severe inflammation, kidney damage, Affect, non-survivor, thought, enrolled, died, significantly, addition, elevated, not affect, conditions, survived, COVID-19 in patient, had more, higher odd, hypertensive patient, patients with COVID-19, subgroup of patient, with COVID-19, 【제목키워드】 outcome, multicentre, retrospective cohort study, Effect,