This is the first report of persistent oropharyngeal mucosal infection with type 2 poliovirus (iVDPV2) in a primary immune deficient patient (PID) after wild type 2 poliovirus eradication. The iVDPV2 also established persistence in the gut. iVDPV2 at both loci evolved independently. Persistent oral infections present a potential risk for oral-oral as well as fecal-oral poliovirus transmission during transition to a poliovirus 2-free world.
All Keywords
【저자키워드】 stools, contact isolation, Droplet isolation, Oropharyngeal mucosa, Primary immune deficiency (PID), Type 2 vaccine-derived poliovirus (iVDPV2),
【저자키워드】 stools, contact isolation, Droplet isolation, Oropharyngeal mucosa, Primary immune deficiency (PID), Type 2 vaccine-derived poliovirus (iVDPV2),