Introduction: The COVID-19 pandemic caused an increased mortality in nursing homes due to its quick spread and the age-related high lethality. Results: We observed a two-month mortality of 40%, compared to 6.4% in the previous year. This increase was seen in both COVID-19 positive (43%) and negative (24%) residents, but 8 patients among those testing negative on the swab, tested positive on serological tests. Increased mortality was associated with male gender, older age, no previous vitamin D supplementation and worse “activities of daily living (ADL)” scores, such as Barthel index, Tinetti scale and S.OS.I.A. classification. Conclusion: Our data confirms a higher geriatric mortality due to COVID-19. Negative residents also had higher mortality, which we suspect is secondary to preanalytical error and a low sensitivity of the swab test in poorly compliant subjects. Male gender, older age and low scores on ADL scales (probably due to immobility) are risk factors for COVID-19 related mortality. Finally, mortality was inversely associated with vitamin D supplementation. Design: In this observational study, we described the two-month mortality among the 157 residents (age 60-100) of a nursing home after Sars-CoV-2 spreading, reporting the factors associated with the outcome. We also compared the diagnostic tests for Sars-CoV-2.
【저자키워드】 COVID-19, Hydroxychloroquine, serology, Nasopharyngeal swab, Sensitivity and specificity, Activities of Daily Living, 【초록키워드】 Mortality, COVID-19 pandemic, diagnostic test, Gender, outcome, risk factor, Spread, sensitivity, male, Patient, Older age, age, Swab, Swab test, serological, Vitamin D supplementation, Factor, daily living, increased mortality, positive, COVID-19 related mortality, negative, tested, described, caused, subjects, Increased, 【제목키워드】 diagnostic test, Gender, age, correlation, Vitamin D supplementation, limitation, Italian,