Background: Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) is the virus responsible for the coronavirus disease 2019(COVID-19) pandemic. Despite the extensive studies aiming to understand the pathology of COVID-19, the clinicopathological characteristics and risk factors associated with COVID-19 remain mostly unclear. In this study, we assessed the clinical course and features of COVID-19 patients. Findings: There were 59 patients (54.1%) that had no fever. One-hundred(91.7%) patients required oxygen therapy, which improved percutaneous oxygen saturation (SpO 2 ). Seventy-two (66.1%) patients aged over 60; these patients were more likely to develop respiratory symptoms. Only 13(11.9%) patients were positive for anti-SARS-CoV-2 antibodies, SARS-CoV-2 nucleic acid, and computed tomography (CT) findings. We found significant differences in age, respiratory symptoms, and heart rates between patients with and without underlying conditions. Conclusions: Our findings suggest that oxygen plays an important role in the treatment of COVID-19 patients and that age and underlying diseases are significant risk factors for COVID-19. Most COVID-19 patients have no fever, and CT provides higher detection rates than antibody- and nucleic acid-based detection methods. Methods: We analyzed data from 109 confirmed COVID-19 cases. We compared the clinicopathological characteristic of patients stratified according to age and underlying diseases, as well as assessed the detection rates of different diagnostic methods.
【저자키워드】 COVID-19, SARS-CoV-2, Risk factors, Infection, Chronic diseases, 【초록키워드】 Treatment, coronavirus disease, pathology, coronavirus, pandemic, antibody, oxygen, underlying disease, risk factor, virus, Computed tomography, oxygen saturation, anti-SARS-CoV-2 antibodies, Clinical course, Characteristics, Fever, Patient, Oxygen therapy, age, diagnostic methods, underlying diseases, characteristic, underlying conditions, detection rate, COVID-19 patients, COVID-19 cases, COVID-19 patient, respiratory symptoms, acute respiratory syndrome, significant difference, SARS-CoV-2 nucleic acid, positive, MOST, feature, responsible, analyzed, develop, required, provide, had no, stratified, with COVID-19, 【제목키워드】 coronavirus disease, clinical, Wuhan, retrospective, Course, characteristics of patient,