Simple Summary Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of the coronavirus disease 2019 (COVID-19) pandemic, is continuing to spread worldwide. As with many emerging infectious diseases, COVID-19 is of zoonotic origin, meaning that animals are susceptible to infection, including domestic pets such as dogs. Despite epidemiological surveys conducted in dogs living either in SARS-CoV-2-positive households or in geographic areas affected by COVID-19 steadily increasing, clinical reports aimed at characterising disease manifestation are currently scant in this species. This case report accurately describes the development of myocardial injury complicated by left ventricular systolic dysfunction in a SARS-CoV-2-positive dog. Interestingly, the clinical picture described herein closely resembles the cardiological compromise documented in SARS-CoV-2-positive humans and can therefore contribute to filling the current knowledge gap that exists between human and veterinary medicine concerning COVID-19. Abstract A six-year-old Cavalier King Charles spaniel was referred with a two-month history of severe exercise intolerance and syncope. Clinical signs had developed during a local wave of coronavirus disease (COVID-19) two weeks after its family members had manifested symptoms of this viral disease and their positivity to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was confirmed. Cardiologic assessment documented myocardial injury complicated by systolic dysfunction. An extensive diagnostic work-up allowed us to rule out common causes of myocardial compromise, both infective and not. Accordingly, serological and molecular tests aimed at diagnosing SARS-CoV-2 infection were subsequently performed, especially in light of the dog’s peculiar history. Results of such tests, interpreted in the light of previous findings and current knowledge from human medicine, supported a presumptive diagnosis of COVID-19-associated myocardial injury, a clinical entity hitherto poorly described in this species.
【저자키워드】 SARS-CoV-2, echocardiography, myocarditis, canine, dilated cardiomyopathy phenotype, 【초록키워드】 COVID-19, coronavirus disease, coronavirus, pandemic, Diseases, knowledge, SARS-COV-2 infection, Human, Infection, diagnostic, Diagnosis, Local, Symptom, Case report, Spread, myocardial injury, clinical picture, epidemiological survey, viral disease, serological, dysfunction, Syncope, acute respiratory syndrome, disease manifestation, diagnosing, molecular test, zoonotic origin, infective, Clinical sign, simple, susceptible, Myocardial, Result, described, performed, affected, conducted, supported, contribute, cause, manifested, concerning, cardiological, characterising, Charle, closely resemble, King, ventricular, 【제목키워드】 dog, systolic,