Background With the spread of SARS-CoV-2 worldwide, understanding the basic epidemiological parameter values of COVID-19 from real-world data in mega-cities is essential for disease prevention and control. Methods To investigate the epidemiological parameters in SARS-CoV-2 infected cases in Beijing, we studied all confirmed cases and close contacts in Beijing from Jan 1st to Apr 3rd 2020. The epidemiological and virological characteristics of SARS-CoV-2 were analyzed. Results A total of 602 cases were positive for SARS-CoV-2, including 585 confirmed patients and 17 asymptomatic infections. The imported cases were mainly from Wuhan initially and then from abroad. Among 585 confirmed case-patients, the median age was 39 years old. The mean incubation period was 6.3 days. The secondary attack rate among households was higher than social contacts (15.6 vs 4.6%). The secondary attack rate of healthcare workers (HCWs) was higher than non-HCWs’ (7.3 vs 4.2%). The basic reproduction number was 2.0, and the average serial interval was 7.6 days. No significant genetic variant was identified. Conclusions The transmissibility of SARS-CoV-2 was relatively high, especially among households and from HCWs, which draws specific public health attention. So far, no evidence of widespread circulation of SARS-CoV-2 in communities in Beijing was found.
【저자키워드】 COVID-19, Epidemiology, secondary attack rate, Transmissibility, 【초록키워드】 public health, SARS-CoV-2, real-world data, healthcare worker, asymptomatic infections, Spread, Characteristics, HCWs, Wuhan, Patient, Community, basic reproduction number, age, epidemiological, Genetic variant, circulation, disease, Evidence, close contact, confirmed case, Virological, Beijing, average, social contact, positive, transmissibility of SARS-CoV-2, parameter, mean incubation period, widespread, Result, analyzed, infected case, the median, 【제목키워드】 China, Characteristics, epidemiological, Beijing, parameter, basic,