We report a case of 4-years-old girl who suffered one episode of clinically typical erythema nodosum and arthralgia of short duration. Stool culture showed growth of Salmonella enteritidis. Levels of serum anti-Salmonella antibodies and immunocomplexes lowered during resolution of skin nodules. Erythema nodosum probably results from the formation of immunocomplexes and their deposition in and around blood vessels of the skin. Salmonellosis should be considered in patients presenting with erythema nodosum. Routine stool culture might provide an important diagnostic clue.
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