Background The Coronavirus Disease 2019 (COVID-19) caused by severe acute respiratory syndrome Coronavirus-2 has spread rapidly worldwide and disease spread is currently increasing. Data on the clinical picture of transplant recipients and management of the anti-rejection immunosuppressive therapy on COVID-19 infection are lacking. Case presentation We report two cases of COVID-19 infection in renal transplant recipients with variable clinical presentations. The first patient presented with mild respiratory symptoms and a stable clinical course. The second patient had more severe clinical characteristics and presented with severe pneumonia and multi-organ failure. Both patients received a combination therapy including antiviral treatment and reduced immunosuppression therapy and finally recovered. Conclusions We report COVID-19 infection in two renal transplant recipients with a favorable outcome but different clinical courses, which may provide a reference value for treating such patients.
【저자키워드】 Coronavirus disease 2019, Case report, immunosuppressive therapy, acute respiratory syndrome coronavirus 2, Renal transplant recipients, 【초록키워드】 COVID-19, therapy, Clinical characteristics, Immunosuppression, combination therapy, Antiviral treatment, outcome, Spread, Clinical course, COVID-19 infection, clinical picture, management, Patient, severe pneumonia, disease spread, patients, immunosuppressive, acute respiratory syndrome, Clinical presentations, multi-organ failure, renal, recipient, courses, caused, reduced, had more, mild respiratory symptom, 【제목키워드】 coronavirus disease, clinical presentation, renal, recipient,