Streptococcus pneumoniae (pneumococcus) is a human pathogen that colonizes the nasopharynx. We investigated serotype distribution in paired invasive and nasopharyngeal samples obtained from 57 children during invasive pneumococcal disease. Of 39 nasopharyngeal samples positive for pneumococci, 46.2% contained a serotype different from the one causing disease. This study reports a high frequency of pneumococcal multiple serotype carriage in children with invasive pneumococcal disease. Whether multiple serotype carriage is important for the onset and progress to pneumococcal infection warrants further investigation.
All Keywords
【저자키워드】 children, Streptococcus pneumoniae, invasive pneumococcal disease, co-colonization, Multiple serotype carriage,
【저자키워드】 children, Streptococcus pneumoniae, invasive pneumococcal disease, co-colonization, Multiple serotype carriage,