Rapid assessment of tetanus vaccine-induced immunity in Bangladesh and the Gambia

Published on 2017-03-312024-09-01
Journal: Diagnostic Microbiology and Infectious Disease

[저자] Girija Ramakrishnan, Marcia Wright, Masud Alam, Caitlin Naylor, Mamun Kabir, Ayesha Zerin, Tahsin Ferdous, Karl Pedersen, Branwen J Hennig, Jeffrey R Donowitz, Rita Wegmuller, Rashidul Haque, William A Petri Jr, Joel Herbein, Carol A Gilchrist

[Category] 파상풍,

Pubmed URL

[Article Type] article

[Source] pubmed

We have developed recombinant fragment C based rapid point of care dipstick devices to assess tetanus immunization status using plasma or whole blood. The devices demonstrated specificity of 0.90 and sensitivity of 0.90 (whole blood)/0.94 (plasma) at field sites in Bangladesh and The Gambia when compared to a commercial ELISA with the immune cut-off titer set as ≥0.1IU/mL.

All Keywords
【저자키워드】 Vaccine, lateral flow, Dipstick, Tetanus, Fragment C,