Coronavirus disease 2019 (COVID-19) is a zoonotic respiratory infection originating from Wuhan, China. Rapidly spreading from Wuhan to all inhabited continents of the world, the World Health Organisation declared COVID-19 a pandemic on March 11, 2019. Infected patients present with fever and cough; radiological features include bilateral infiltrates on chest x-ray and computed tomography scanning. Management is supportive with oxygen supplementation, broad-spectrum antibiotics as well as careful fluid balancing. A number of drugs, both new and old, are currently in clinical trials and being used on an experimental basis in clinical practice. The COVID-19 pandemic is the greatest worldwide public health crisis of a generation, and has led to seismic political, economic and social changes. This review provides an overview of COVID-19 for junior doctors who find themselves on a new frontline of healthcare. Highlights • Coronavirus disease 2019 is a zoonotic respiratory infection that rapidly spread from China to become a pandemic. • The most common symptoms are cough, fever and shortness of breath; infection typically produces mild symptoms. • A minority of patients have severe symptoms, such as respiratory failure, which requires hospital admission and even intensive care unit admission. • Guidelines suggest that the management of coronavirus disease 2019, in most cases, is supportive • Several agents, such as hydroxychloroquine, azithromycin and remdesivir are currently under investigation as treatment for the disease.
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