Introduction the COVID-19 pandemic still accounts for thousands of cases every day. It’s neurological involvement has been well documented most likely due to auto-immune mechanisms than the virus itself. Case report we report the case of a 38 years old women who developed an Acute Disseminated Encephalomyelitis following a COVID-19 infection, with a favorable outcome after immunosuppressive therapy. Discussion In this chapter, we discuss ADEM’s pathogenesis as well as its clinical and radiological features before detailing its relationship with infectious and vaccination episodes. We also discuss how our patient disease evolved. Conclusion Acute Disseminated Encephalomyelitis is an immune-mediated disorder in which the widespread inflammation of the brain and spinal cord is responsible for a variety of symptoms. The novel COVID-19 virus and its vaccine are both a newly incriminated etiologies of this demyelinating disorder. Highlights • COVID-19 neurotropism has been well established and its neurological manifestations are varied. • Demyelinating disorders are immune-induced disease most likely due to an antigenic analogy between the virus and myelin constituents. • COVID-19 induced ADEM is extremely rare, only a dozen cases have been reported worldwide, and ours is the only case reported in our country.
【저자키워드】 COVID-19, ADEM, neurotropism, 【초록키워드】 Inflammation, Vaccine, vaccination, therapy, Pathogenesis, COVID-19 pandemic, outcome, virus, Symptoms, Brain, COVID-19 infection, Patient, COVID-19 virus, women, etiology, disease, mechanism, Immune-mediated, Neurological involvement, immunosuppressive, Encephalomyelitis, demyelinating, antigenic, disorder, neurological manifestation, widespread, country, responsible, reported, variety, demyelinating disorder, radiological feature,